carbamazepine


SMILES NC(=O)N1c2ccccc2C=Cc2c1cccc2
InChIKey FFGPTBGBLSHEPO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 236.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FZD8 FZD8 Mouse Frizzled F pKd 4.78 4.78 4.78 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
H1 HRH1 Human Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
H1 HRH1 Human Histamine A pKi 8.38 8.38 8.38 Drug Central
FZD8 FZD8 Human Frizzled F pKd 8.32 8.32 8.32 Drug Central
D1 DRD1 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
FZD8 FZD8 Human Frizzled F pKd 4.77 4.77 4.77 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TSH TSHR Human Glycoprotein hormone A Potency 5.2 5.2 5.2 ChEMBL