CHEMBL199876


SMILES O=c1[nH]c2[nH]c(-c3ccc(Cl)cc3)cc2c(=O)n1CCN1CCN(c2ccccc2Cl)CC1
InChIKey XRHMVCVKZQLVNP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 483.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.62 5.62 5.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database