CHEMBL212912


SMILES CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3ccccc3Cl)c3ccccc32)CC1
InChIKey DDNAXKKEJCCHMD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 479.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.14 7.14 7.14 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.34 6.34 6.34 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.39 8.39 8.4 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.74 6.74 6.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database