CHEMBL213492


SMILES CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3c(F)cccc3C(F)(F)F)c3ccccc32)CC1
InChIKey FFNDTETUPMNYNN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 531.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 8.15 8.15 8.15 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.7 5.7 5.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.7 5.7 5.7 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.6 8.6 8.6 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.92 8.92 8.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database