CXCL12α
SMILES | None |
InChIKey | None |
Sequence | KPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNK |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | No |
Database connections
Structure pdb | 7SK3 |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CXCR3 | CXCR3 | Human | Chemokine | A | pKi | 6.4 | 6.4 | 6.4 | Guide to Pharmacology |
CXCR4 | CXCR4 | Human | Chemokine | A | pKd | 7.7 | 7.95 | 8.2 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CXCR4 | CXCR4 | Human | Chemokine | A | pIC50 | 9.3 | 9.3 | 9.3 | Guide to Pharmacology |
ACKR3 | ACKR3 | Human | Chemokine | A | pEC50 | 7.52 | 7.71 | 7.9 | Guide to Pharmacology |