CHEMBL213912
SMILES | CN1CCN(C2=Nc3ccc(Cl)cc3Oc3ccccc32)CC1 |
InChIKey | FSRSEANZUZHDHK-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 0 |
Molecular weight (Da) | 327.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H4 | HRH4 | Human | Histamine | A | pKi | 6.99 | 7.58 | 8.22 | ChEMBL |
H4 | HRH4 | Human | Histamine | A | pKd | 7.14 | 7.66 | 7.97 | ChEMBL |
H2 | HRH2 | Human | Histamine | A | pKi | 5.06 | 5.06 | 5.06 | ChEMBL |
H1 | HRH1 | Human | Histamine | A | pKi | 8.08 | 8.1 | 8.11 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 5.04 | 5.04 | 5.04 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H4 | HRH4 | Human | Histamine | A | pEC50 | 7.7 | 7.7 | 7.7 | ChEMBL |
H1 | HRH1 | Human | Histamine | A | pEC50 | 8.17 | 8.17 | 8.17 | ChEMBL |