CHEMBL215576


SMILES CNC(=O)[C@H](Cc1ccc2ccccc2c1)N1CCN(C(=O)CCc2ccc(F)cc2)[C@@H](CCCN=C(N)N)C1=O
InChIKey SJRCSWXLNHDZIX-SVBPBHIXSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 560.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 6.02 6.02 6.02 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.69 6.69 6.69 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.28 8.28 8.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 5.86 5.86 5.86 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 6.85 6.85 6.85 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 8.05 8.05 8.05 ChEMBL