cyclosporin A
SMILES | None |
InChIKey | PMATZTZNYRCHOR-CGLBZJNRSA-N |
Sequence | XXXLVLAALLV |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Surrogate |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
NK2 | NK2R | Human | Tachykinin | A | pKi | 5.86 | 5.86 | 5.86 | ChEMBL |
NK2 | NK2R | Human | Tachykinin | A | pKi | 8.23 | 8.23 | 8.23 | Drug Central |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
FPR1 | FPR1 | Human | Formylpeptide | A | pEC50 | 6.2 | 6.25 | 6.3 | Guide to Pharmacology |
NK2 | NK2R | Human | Tachykinin | A | pIC50 | 5.38 | 5.38 | 5.38 | ChEMBL |
FPR1 | FPR1 | Human | Formylpeptide | A | pEC50 | 8.2 | 8.2 | 8.2 | Drug Central |