CHEMBL2159459


SMILES O=S(=O)(NCC1CCN(CCOc2cccc(F)c2)CC1)c1ccc(F)cc1
InChIKey NTXUZPFGBADASP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 410.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.87 5.87 5.87 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.67 5.67 5.67 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.04 6.04 6.04 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.08 6.08 6.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database