TAK-448 [8159]



TAK-448

No image available
SMILES CN=C(N)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
InChIKey MWXWMWSUUYXMRA-GRKBUMBKSA-N
Sequence None

Chemical Properties

Hydrogen bond acceptors 15
Hydrogen bond donors 17
Rotatable bonds 30
Log P -3.407
Molecular weight (Da) 1224.6
Stereochemistry info partial

Database connections

Structure pdb 8ZJE

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

TAK-448

No image available

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Structure pdb 8ZJE

Compound is not listed as a drug.