tenofovir alafenamide [8233]
tenofovir alafenamide
| SMILES | CC(C)OC(=O)[C@H](C)N[P@](=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)Oc1ccccc1 |
| InChIKey | LDEKQSIMHVQZJK-CAQYMETFSA-N |
Chemical Properties
| Hydrogen bond acceptors | 10 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 11 |
| Log P | 2.973 |
| Molecular weight (Da) | 476.2 |
| Stereochemistry info | partial |
Database connections
No bioactivity data available.
tenofovir alafenamide
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Distribution across phases (no. indications)
Phase I
0
Phase II
0
Phase III
0
Phase IV
0