CHEMBL2181170


SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1
InChIKey JBPBJYKHTQKMKP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 10.4 10.4 10.4 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.71 5.71 5.71 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.87 6.87 6.87 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.31 6.31 6.31 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database