dynorphin A-(1-8)
SMILES | None |
InChIKey | WRPLGMBDXVBPEG-VGXZEHLRSA-N |
Sequence | YGGFLRRI |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
δ | OPRD | Human | Opioid | A | pKi | 8.4 | 8.4 | 8.4 | Guide to Pharmacology |
μ | OPRM | Human | Opioid | A | pKi | 8.4 | 8.4 | 8.4 | Guide to Pharmacology |
μ | OPRM | Human | Opioid | A | pKi | 7.45 | 7.45 | 7.45 | ChEMBL |
δ | OPRD | Human | Opioid | A | pKi | 8.07 | 8.07 | 8.07 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 8.34 | 8.34 | 8.34 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 8.0 | 8.95 | 9.9 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
κ | OPRK | Mouse | Opioid | A | pIC50 | 9.7 | 9.7 | 9.7 | Guide to Pharmacology |