EFPPEA


SMILES CCc1nn2c(c1CCNC(=O)C)c1CCOc1cc2
InChIKey IZDHETWMKYCGAU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 273.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT1 MTR1A Human Melatonin A pKi 10.2 10.2 10.2 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 9.4 9.4 9.4 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 9.38 9.38 9.38 ChEMBL
MT1 MTR1A Human Melatonin A pKi 10.21 10.21 10.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT2 MTR1B Human Melatonin A pEC50 9.28 9.28 9.28 ChEMBL
MT1 MTR1A Human Melatonin A pEC50 10.68 10.68 10.68 ChEMBL