CHEMBL2206890


SMILES CC(C)N(Cc1cnc[nH]1)c1cccc(Cl)c1
InChIKey UQYBANUOFYJXRZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 249.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Human Trace amine A pKi 8.4 8.4 8.4 ChEMBL
TA1 TAAR1 Mouse Trace amine A pKi 8.92 8.92 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Rat Trace amine A pEC50 7.57 7.57 7.57 ChEMBL
TA1 TAAR1 Human Trace amine A pEC50 8.34 8.34 8.34 ChEMBL
TA1 TAAR1 Mouse Trace amine A pEC50 8.0 8.0 8.0 ChEMBL