forasartan
| SMILES | CCCCc1nc(nn1Cc1ccc(nc1)c1ccccc1c1n[nH]nn1)CCCC |
| InChIKey | YONOBYIBNBCDSJ-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 7 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 10 |
| Molecular weight (Da) | 416.2 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| AT1 | AGTR1 | Human | Angiotensin | A | pKd | 8.2 | 8.2 | 8.2 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| AT1 | AGTRB | Rat | Angiotensin | A | pIC50 | 8.2 | 8.4 | 8.6 | Guide to Pharmacology |
| AT1 | AGTR1 | Human | Angiotensin | A | pIC50 | 8.16 | 8.16 | 8.16 | ChEMBL |
| AT1 | AGTRB | Rat | Angiotensin | A | pIC50 | 8.16 | 8.16 | 8.16 | ChEMBL |