GPCRdb

CHEMBL222371

SMILES	CC(Oc1ccccc1-c1cccc(N)c1)C1=NCCN1
InChIKey	YVSAGYHRJDVYHG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	4
Molecular weight (Da)	281.2

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	7.43	7.43	7.43	ChEMBL
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	6.32	6.32	6.32	ChEMBL
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	6.51	6.51	6.51	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
α_2A	ADA2A	Human	Adrenoceptors	A	pEC50	6.59	6.59	6.59	ChEMBL
α_2C	ADA2C	Human	Adrenoceptors	A	pEC50	6.3	6.3	6.3	ChEMBL

Showing 1 to 2 of 2 entries