CHEMBL223289


SMILES COc1ccc(Cl)cc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccccc43)c2=O)CC1
InChIKey CQVOUGAYKKUSBQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 470.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 7.27 7.27 7.27 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.04 7.04 7.04 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.87 7.87 7.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database