furosemide
| SMILES | OC(=O)c1cc(c(cc1NCc1ccco1)Cl)S(=O)(=O)N |
| InChIKey | ZZUFCTLCJUWOSV-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 3 |
| Rotatable bonds | 5 |
| Molecular weight (Da) | 330.0 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GPR35 | GPR35 | Human | A orphans | A | pKi | 5.49 | 5.49 | 5.49 | ChEMBL |
| GPR35 | GPR35 | Human | A orphans | A | pKi | 8.26 | 8.26 | 8.26 | Drug Central |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GPR35 | GPR35 | Human | A orphans | A | pEC50 | 5.21 | 5.42 | 5.63 | Guide to Pharmacology |
| GPR35 | GPR35 | Human | A orphans | A | pEC50 | 4.95 | 5.08 | 5.21 | ChEMBL |