Chembl228280

Chemical Properties

SMILES O=S(=O)(N[C@H]1CC[C@@H](N2CCC(c3ccccc3OC3CC3)CC2)CC1)c1cc(Cl)ccc1F
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight 506.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey LVDRNYWTLKUNNT-OYRHEFFESA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.97 6.97 6.97 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.74 8.74 8.74 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.68 8.68 8.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.73 6.73 6.73 ChEMBL