CHEMBL223836


SMILES CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1
InChIKey OOYTZYZXCMCMSZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 284.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 7.77 7.77 7.77 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.83 7.83 7.83 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 7.22 7.22 7.22 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 6.98 6.98 6.98 ChEMBL