UFP-112 [8536]
UFP-112
| SMILES | C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C(C)(C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(N)=O |
| InChIKey | GVIRJSRJRJCCJE-HCYVKCTOSA-N |
| Sequence | FGGFTGXRKSARKRKNQ |
| HELM | PEPTIDE1{F.G.G.[X3].T.G.[Aib].R.K.S.A.R.K.R.K.N.Q.[am]}$$$$ |
Chemical Properties
| Hydrogen bond acceptors | 28 |
| Hydrogen bond donors | 34 |
| Rotatable bonds | 68 |
| Log P | -12.805 |
| Molecular weight (Da) | 1939.1 |
| Stereochemistry info | partial |
Database connections
| Model (AF2) | NOP |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Protein | Gene | Species | Family | Class | Type | Min | Avg | Max | Database |
UFP-112
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Distribution across phases (no. indications)
Phase I
0
Phase II
0
Phase III
0
Phase IV
0
Database connections
| Model (AF2) | NOP |