CHEMBL226166


SMILES Oc1ccc2c(c1)[C@]13CCN(CC4CC4)[C@H](C2)[C@@H]1Cc1c([nH]c2ccccc12)C3
InChIKey HUJCCTOSCFPUOT-HDYLNDSGSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 384.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.72 9.72 9.72 ChEMBL
κ OPRK Human Opioid A pKi 9.19 9.19 9.19 ChEMBL
μ OPRM Human Opioid A pKi 8.96 8.96 8.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 8.92 8.92 8.92 ChEMBL
δ OPRD Human Opioid A pEC50 9.8 9.8 9.8 ChEMBL
κ OPRK Human Opioid A pIC50 7.77 7.77 7.77 ChEMBL
κ OPRK Human Opioid A pEC50 7.21 7.21 7.21 ChEMBL
μ OPRM Human Opioid A pIC50 7.92 7.92 7.92 ChEMBL
μ OPRM Human Opioid A pEC50 7.04 7.04 7.04 ChEMBL