GnRH I
| SMILES | None |
| InChIKey | NMJREATYWWNIKX-UHFFFAOYSA-N |
| Sequence | XHWSYGLRPG |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Endogenous |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GnRH1 | GNRHR | Rat | Gonadotrophin-releasing hormone | A | pKi | 6.8 | 6.8 | 6.8 | Guide to Pharmacology |
| GnRH1 | GNRHR | Human | Gonadotrophin-releasing hormone | A | pKi | 7.3 | 8.0 | 8.4 | Guide to Pharmacology |
| GnRH1 | GNRHR | Human | Gonadotrophin-releasing hormone | A | pKd | 7.66 | 8.1 | 8.54 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| GnRH1 | GNRHR | Rat | Gonadotrophin-releasing hormone | A | pIC50 | 7.7 | 7.7 | 7.7 | Guide to Pharmacology |
| GnRH1 | GNRHR | Mouse | Gonadotrophin-releasing hormone | A | pEC50 | 7.77 | 7.85 | 7.92 | Guide to Pharmacology |
| GnRH1 | GNRHR | Mouse | Gonadotrophin-releasing hormone | A | pIC50 | 8.3 | 8.3 | 8.3 | Guide to Pharmacology |
| GnRH1 | GNRHR | Human | Gonadotrophin-releasing hormone | A | pEC50 | 10.0 | 10.0 | 10.0 | Guide to Pharmacology |
| GnRH1 | GNRHR | Human | Gonadotrophin-releasing hormone | A | pIC50 | 8.6 | 8.6 | 8.6 | Guide to Pharmacology |