icatibant


SMILES None
InChIKey QURWXBZNHXJZBE-MCDGZUPGSA-N
Sequence RRPXGXSXXR

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pKi 6.4 6.7 7.0 Guide to Pharmacology
B2 BKRB2 Human Bradykinin A pKi 10.19 10.19 10.19 Guide to Pharmacology
B2 BKRB2 Mouse Bradykinin A pKi 9.6 9.6 9.6 Guide to Pharmacology
B1 BKRB1 Rat Bradykinin A pKi 6.1 6.25 6.4 Guide to Pharmacology
B2 BKRB2 Rat Bradykinin A pKi 10.0 10.15 10.3 Guide to Pharmacology
B2 BKRB2 Rat Bradykinin A pKd 9.5 9.5 9.5 ChEMBL
B2 BKRB2 Rat Bradykinin A pKi 10.11 10.11 10.11 ChEMBL
B2 BKRB2 Human Bradykinin A pKd 9.04 9.29 9.55 ChEMBL
B2 BKRB2 Human Bradykinin A pKi 9.1 9.97 10.6 ChEMBL
B2 BKRB2 Guinea pig Bradykinin A pKi 9.96 9.96 9.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B2 BKRB2 Human Bradykinin A pA2 8.4 8.4 8.4 Guide to Pharmacology
B2 BKRB2 Human Bradykinin A pIC50 8.0 8.7 9.4 Guide to Pharmacology
B2 BKRB2 Human Bradykinin A pIC50 8.48 8.89 9.31 ChEMBL
B2 BKRB2 Guinea pig Bradykinin A pIC50 8.27 9.48 10.05 ChEMBL