Chembl2364978


SMILES CN(CCC[C@]1(O)[C@H]2CCN(C)[C@@H]1Cc1ccc(O)c(O)c12)C(=O)/C=C/c1ccoc1
InChIKey XWEIVFWMWDDUCW-KVBLMNPTSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 8.56 8.56 8.56 ChEMBL
δ OPRD Mouse Opioid A pKi 7.45 7.45 7.45 ChEMBL
κ OPRK Guinea pig Opioid A pKi 9.13 9.13 9.13 ChEMBL
κ OPRK Human Opioid A pEC50 7.95 7.95 7.95 ChEMBL