CHEMBL216393


SMILES Cc1cccc(NC(=O)CN2CCC(c3ccccc3)CC2)c1
InChIKey ZMEYWYCGMCZGRN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 308.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.59 8.22 8.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.11 6.24 6.36 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.09 6.5 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 6.62 7.07 7.81 ChEMBL
D4 DRD4 Human Dopamine A pIC50 6.87 7.79 8.7 ChEMBL
D2 DRD2 Human Dopamine A pIC50 4.78 4.95 5.11 ChEMBL