Chembl236676

Chemical Properties

SMILES CNCc1cc(C#CCCN2CCOCC2)ccc1Oc1ccc(Cl)c(C(F)(F)F)c1
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight 452.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey MFLUAACJGOHFDP-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 7.89 7.89 7.89 ChEMBL
H3 HRH3 Human Histamine A pKd 7.89 7.89 7.89 ChEMBL
H3 HRH3 Human Histamine A pKi 6.89 6.89 6.89 PDSP KiDatabase