CHEMBL237191


SMILES Cc1nc(N2CCCC2)ncc1-c1ccc2cc(CCN3CCC[C@H]3C)ccc2n1
InChIKey DWAOPDWPKFXRII-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 401.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.71 9.03 9.14 ChEMBL
H3 HRH3 Human Histamine A pKi 9.52 9.54 9.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pEC50 8.52 8.52 8.52 ChEMBL
H3 HRH3 Human Histamine A pEC50 9.11 9.11 9.11 ChEMBL