CHEMBL2380386


SMILES COc1cccc(CCC(=O)Nc2nc3ccccc3c(=O)s2)c1
InChIKey YPRGLOMMHZBVJQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 340.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKi 6.53 6.53 6.53 ChEMBL
A1 AA1R Rat Adenosine A pKi 6.43 6.43 6.43 ChEMBL
A2B AA2BR Human Adenosine A pKi 6.65 6.65 6.65 ChEMBL
A3 AA3R Human Adenosine A pKi 6.76 6.76 6.76 ChEMBL
A2A AA2AR Human Adenosine A pKi 7.19 7.19 7.19 ChEMBL
A1 AA1R Human Adenosine A pKi 5.86 5.86 5.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database