PF-03654746


SMILES CCNC(=O)C1CC(C1)(F)c1ccc(c(c1)F)CN1CCCC1
InChIKey SXMBKHYDZOCBMT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 5.63 5.63 5.63 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.06 5.06 5.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database