Chembl241497
Chemical Properties
| SMILES | COC(=O)[C@H](CCCNC(=N)N)NC(=O)CCCc1cc(-c2cc(Cl)cc(Cl)c2)nn1-c1ccc2ccccc2c1 |
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 4 |
| Rotatable bonds | 12 |
| Molecular weight | 594.2 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | YLNOGPJREAMGJN-SANMLTNESA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CCR5 | CCR5 | Human | Chemokine | A | pIC50 | 7.2 | 7.2 | 7.2 | ChEMBL |
| CCR2 | CCR2 | Human | Chemokine | A | pIC50 | 6.66 | 6.7 | 6.73 | ChEMBL |