LPA


SMILES CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O
InChIKey WRGQSWVCFNIUNZ-KTKRTIGZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 20
Molecular weight (Da) 436.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
LPA3 LPAR3 Human Lysophospholipid (LPA) A pKd 6.69 6.69 6.69 Guide to Pharmacology
LPA4 LPAR4 Human Lysophospholipid (LPA) A pKd 7.35 7.35 7.35 Guide to Pharmacology
LPA5 LPAR5 Human Lysophospholipid (LPA) A pKd 8.19 8.19 8.19 Guide to Pharmacology
LPA4 LPAR4 Mouse Lysophospholipid (LPA) A pKd 7.35 7.35 7.35 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
LPA2 LPAR2 Human Lysophospholipid (LPA) A pEC50 6.71 7.44 8.16 Guide to Pharmacology
LPA5 LPAR5 Human Lysophospholipid (LPA) A pEC50 4.3 6.1 7.9 Guide to Pharmacology
LPA6 LPAR6 Human Lysophospholipid (LPA) A pEC50 6.0 6.0 6.0 Guide to Pharmacology
GPR87 GPR87 Human A orphans A pEC50 7.44 7.44 7.44 Guide to Pharmacology
P2RY10 P2Y10 Human A orphans A pEC50 6.9 6.9 6.9 Guide to Pharmacology
LPA1 LPAR1 Mouse Lysophospholipid (LPA) A pEC50 7.9 8.1 8.3 Guide to Pharmacology
LPA2 LPAR2 Mouse Lysophospholipid (LPA) A pEC50 8.0 8.09 8.17 Guide to Pharmacology
LPA3 LPAR3 Mouse Lysophospholipid (LPA) A pEC50 6.6 6.6 6.6 Guide to Pharmacology
LPA2 LPAR2 Human Lysophospholipid (LPA) A pEC50 8.52 8.52 8.52 ChEMBL
LPA3 LPAR3 Human Lysophospholipid (LPA) A pEC50 6.54 6.54 6.54 ChEMBL
LPA1 LPAR1 Human Lysophospholipid (LPA) A pEC50 7.1 7.1 7.1 ChEMBL
LPA4 LPAR4 Human Lysophospholipid (LPA) A pEC50 6.24 6.24 6.24 ChEMBL
LPA5 LPAR5 Human Lysophospholipid (LPA) A pEC50 6.85 6.85 6.85 ChEMBL
LPA6 LPAR6 Mouse Lysophospholipid (LPA) A pEC50 6.0 6.0 6.0 Guide to Pharmacology