CHEMBL222466


SMILES COc1cc2c(cc1Cl)[C@@H]1CNCCN1C2=O
InChIKey NBIPHDGFUDLWID-JTQLQIEISA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 252.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.63 5.63 5.63 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.61 6.61 6.61 ChEMBL