LXA4
SMILES | CCCCC[C@@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)O)O |
InChIKey | IXAQOQZEOGMIQS-SSQFXEBMSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 4 |
Rotatable bonds | 14 |
Molecular weight (Da) | 352.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Endogenous |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
FPR2/ALX | FPR2 | Human | Formylpeptide | A | pKd | 8.77 | 9.04 | 9.3 | Guide to Pharmacology |
FPR2/ALX | FPRS1 | Mouse | Formylpeptide | A | pKd | 8.82 | 8.82 | 8.82 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
FPR2/ALX | FPR2 | Human | Formylpeptide | A | pEC50 | 12.0 | 12.0 | 12.0 | Guide to Pharmacology |
GPR32 | GPR32 | Human | A orphans | A | pEC50 | 9.7 | 9.7 | 9.7 | Guide to Pharmacology |
FPR2/ALX | FPR2 | Human | Formylpeptide | A | pIC50 | 7.58 | 8.13 | 8.77 | ChEMBL |