CHEMBL242003
SMILES | Cc1ccc(C2CCN(Cc3ccc(Oc4ccc(F)c(F)c4)cc3)CC2)cc1NC(=O)C(C)C |
InChIKey | ZYUVYNFTIYISBW-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 1 |
Rotatable bonds | 7 |
Molecular weight (Da) | 478.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
MCH1 | MCHR1 | Rat | Melanin-concentrating hormone | A | pKi | 7.57 | 7.57 | 7.57 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.4 | 6.4 | 6.4 | ChEMBL |
α1A | ADA1A | Human | Adrenoceptors | A | pKi | 6.0 | 6.0 | 6.0 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
MCH1 | MCHR1 | Rat | Melanin-concentrating hormone | A | pIC50 | 6.44 | 6.44 | 6.44 | ChEMBL |