Chembl2440611

Chemical Properties

SMILES O=C(Nc1cccc(Cl)n1)c1cc(F)cc(Oc2cncnc2)c1
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight 344.0

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey XWHLYYMBZGRJKE-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.35 7.35 7.35 ChEMBL