α-helical CRF
| SMILES | None |
| InChIKey | TYEPJUPPTULOKD-GVKLFNHCSA-N |
| Sequence | DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pKi | 4.35 | 4.35 | 4.35 | Guide to Pharmacology |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pKi | 8.36 | 8.36 | 8.36 | Drug Central |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CaS | CASR | Human | Calcium-sensing | C | pEC50 | 7.3 | 7.3 | 7.3 | Guide to Pharmacology |
| CaS | CASR | Human | Calcium-sensing | C | pKB | 5.9 | 6.25 | 6.6 | Guide to Pharmacology |
| CaS | CASR | Human | Calcium-sensing | C | pEC50 | 6.75 | 7.18 | 7.7 | ChEMBL |
| CaS | CASR | Human | Calcium-sensing | C | pEC50 | 8.11 | 8.11 | 8.11 | Drug Central |