MAP4


SMILES OC(=O)[C@](CCP(=O)(O)O)(N)C
InChIKey HONKEGXLWUDTCF-YFKPBYRVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 197.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu4 GRM4 Rat Metabotropic glutamate C pKi 4.6 4.6 4.6 Guide to Pharmacology
mGlu7 GRM7 Human Metabotropic glutamate C pKi 3.8 3.8 3.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Rat Metabotropic glutamate C pIC50 3.5 3.5 3.5 Guide to Pharmacology
mGlu8 GRM8 Rat Metabotropic glutamate C pIC50 5.1 6.35 7.6 Guide to Pharmacology