[Met]enkephalin
SMILES | None |
InChIKey | YFGBQHOOROIVKG-FKBYEOEOSA-N |
Sequence | YGGFM |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
κ | OPRK | Rat | Opioid | A | pKi | 6.0 | 6.0 | 6.0 | Guide to Pharmacology |
NOP | OPRX | Guinea pig | Opioid | A | pKi | 6.56 | 6.56 | 6.56 | ChEMBL |
μ | OPRM | Rat | Opioid | A | pKi | 7.56 | 7.63 | 7.7 | ChEMBL |
δ | OPRD | Human | Opioid | A | pKi | 8.7 | 8.83 | 8.96 | ChEMBL |
μ | OPRM | Human | Opioid | A | pKi | 7.72 | 7.72 | 7.72 | ChEMBL |
μ | OPRM | Rat | Opioid | A | pKi | 9.2 | 9.2 | 9.2 | Guide to Pharmacology |
κ | OPRK | Guinea pig | Opioid | A | pKi | 5.35 | 5.35 | 5.35 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
δ | OPRD | Mouse | Opioid | A | pIC50 | 7.4 | 7.4 | 7.4 | Guide to Pharmacology |
δ | OPRD | Mouse | Opioid | A | pIC50 | 7.89 | 7.89 | 7.89 | ChEMBL |
μ | OPRM | Rat | Opioid | A | pIC50 | 8.7 | 8.7 | 8.7 | ChEMBL |
μ | OPRM | Rat | Opioid | A | pEC50 | 6.51 | 6.51 | 6.52 | ChEMBL |
δ | OPRD | Human | Opioid | A | pEC50 | 7.33 | 8.44 | 8.99 | ChEMBL |
δ | OPRD | Human | Opioid | A | pIC50 | 8.19 | 8.19 | 8.19 | ChEMBL |
μ | OPRM | Human | Opioid | A | pIC50 | 7.89 | 7.89 | 7.89 | ChEMBL |
μ | OPRM | Human | Opioid | A | pEC50 | 6.21 | 6.21 | 6.21 | ChEMBL |