MeTRH


SMILES O=C(N1CCC[C@H]1C(=O)N)[C@@H](NC(=O)[C@@H]1CCC(=O)N1C)Cc1[nH]cnc1
InChIKey DJLHRAHTTSWYAW-AVGNSLFASA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 376.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TRH1 TRHR Rat Thyrotropin-releasing hormone A pKd 8.5 8.5 8.5 Guide to Pharmacology
TRH1 TRFR Human Thyrotropin-releasing hormone A pKi 8.5 8.5 8.5 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database