SKF-38393


SMILES Oc1cc2CCNCC(c2cc1O)c1ccccc1
InChIKey JUDKOGFHZYMDMF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 1
Molecular weight (Da) 255.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETA EDNRA Human Endothelin A pKi 9.89 9.89 9.89 Guide to Pharmacology
ETB EDNRB Human Endothelin A pKi 6.76 6.76 6.76 Guide to Pharmacology
ETB EDNRB Human Endothelin A pKi 6.76 6.76 6.76 ChEMBL
ETA EDNRA Human Endothelin A pKi 9.89 9.89 9.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETA EDNRA Human Endothelin A pA2 9.5 9.5 9.5 Guide to Pharmacology
ETB EDNRB Human Endothelin A pIC50 6.76 6.76 6.76 ChEMBL
ETA EDNRA Human Endothelin A pIC50 8.77 8.77 8.77 ChEMBL