CHEMBL232075


SMILES OC1(c2ccccc2CN2CCNCC2)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1
InChIKey ROLCHVRRPRQQIU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 509.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.72 8.72 8.72 ChEMBL
δ OPRD Human Opioid A pKi 5.93 5.93 5.93 ChEMBL
κ OPRK Human Opioid A pKi 6.58 6.58 6.58 ChEMBL
μ OPRM Human Opioid A pKi 6.84 6.84 6.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database