CHEMBL248457


SMILES Cc1ccc2c(OCCN3CCN(Cc4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1
InChIKey JXYPPXBLBAOPFD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 432.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.2 8.0 8.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database