CHEMBL253158


SMILES O[C@H]1CCCc2nc(C#Cc3ccccc3)ccc21
InChIKey VUDNTKZUIAXLLZ-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 249.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 5.03 5.03 5.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 6.6 6.6 6.6 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 5.97 5.97 5.97 ChEMBL