CHEMBL256637


SMILES COc1cc(CN2CCN(c3ccc(Cl)cc3)CC2)c(OCCF)cc1OC
InChIKey XBXGSRGFTFVODB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.77 8.77 8.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.41 5.41 5.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.12 6.12 6.12 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.46 5.46 5.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database