compound 5c [PMID: 27894870]


SMILES OC(=O)CCCNCc1cc2c(s1)c(ccc2)c1ccc2c(c1)cccc2
InChIKey XDCOYBQVEVSNNB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 375.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 5.17 5.17 5.17 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 7.89 7.89 7.89 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 8.6 8.6 8.6 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.23 8.23 8.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database