GPCRdb

FENDILINE

Agent/drug
Bioactivity

FENDILINE

SMILES	CC(NCCC(c1ccccc1)c1ccccc1)c1ccccc1
InChIKey	NMKSAYKQLCHXDK-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	1
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	315.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	5.49	5.49	5.49	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	8.26	8.26	8.26	Drug Central

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CaS	CASR	Human	Calcium-sensing	C	pEC50	6.00	6.00	6.00	ChEMBL
CaS	CASR	Human	Calcium-sensing	C	pEC50	8.22	8.22	8.22	Drug Central
CaS	CASR	Bovine	Calcium-sensing	C	pEC50	8.31	8.31	8.31	Drug Central
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pIC50	5.51	5.51	5.51	ChEMBL
NPS	NPSR1	Human	Neuropeptide S	A	Potency	5.00	5.00	5.00	ChEMBL

Showing 1 to 5 of 5 entries

FENDILINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.