GPCRdb

cloprostenol

Agent/drug
Bioactivity

cloprostenol

SMILES	O=C(O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)COc1cccc(Cl)c1
InChIKey	VJGGHXVGBSZVMZ-QIZQQNKQSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	4
Rotatable bonds	11
Molecular weight (Da)	424.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb
Structure pdb	8XJK 8XJN

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

DP₁	PD2R	Human	Prostanoid	A	pKi	4.80	4.80	4.80	Guide to Pharmacology
EP₁	PE2R1	Human	Prostanoid	A	pKi	5.90	6.00	6.10	Guide to Pharmacology
EP₃	PE2R3	Human	Prostanoid	A	pKi	8.36	8.36	8.36	Guide to Pharmacology
FP	PF2R	Human	Prostanoid	A	pKi	9.30	9.30	9.30	Guide to Pharmacology
FP	PF2R	Human	Prostanoid	A	pKi	7.51	7.51	7.51	ChEMBL
TP	TA2R	Human	Prostanoid	A	pKi	5.20	5.20	5.20	Guide to Pharmacology

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₁	PE2R1	Human	Prostanoid	A	pEC50	6.12	6.12	6.12	ChEMBL
EP₁	PE2R1	Human	Prostanoid	A	pIC50	6.30	6.30	6.30	ChEMBL
EP₂	PE2R2	Human	Prostanoid	A	pIC50	5.43	5.43	5.43	ChEMBL
EP₃	PE2R3	Human	Prostanoid	A	pEC50	6.66	6.66	6.66	Guide to Pharmacology
EP₃	PE2R3	Human	Prostanoid	A	pIC50	6.20	6.20	6.20	ChEMBL
EP₃	PE2R3	Human	Prostanoid	A	pEC50	5.30	5.30	5.30	ChEMBL
FP	PF2R	Human	Prostanoid	A	pEC50	8.00	8.00	8.00	ChEMBL
FP	PF2R	Human	Prostanoid	A	pIC50	8.70	8.85	9.00	ChEMBL
TP	TA2R	Human	Prostanoid	A	pEC50	5.62	5.62	5.62	ChEMBL

Showing 1 to 9 of 9 entries

cloprostenol

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb
Structure pdb	8XJK 8XJN

Compound is not listed as a drug.