CHEMBL112833


SMILES C#Cc1cc(C(=O)N[C@@H]2CCN(Cc3ccccc3)C2)c(OC)c2ccccc12
InChIKey GLJZGPDTNBDSGN-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 384.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.21 5.35 5.48 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.15 8.38 8.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.07 7.08 7.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.3 6.68 7.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database